Expert-backed Formulation
At Iatrogenix, we are committed to transparency and scientific rigor.
Crafted in collaboration with healthcare providers specializing in headache and neurology, our formulation reflects a deep understanding of the underlying science and patient experience.
This section provides references to peer-reviewed studies and systematic reviews that explore the ingredients used in our formulations, highlighting the evidence-based rationale behind MigraMute™ and TurBalance™.
These references focus on human studies where available, supplemented by relevant animal studies when human data is limited. We encourage customers to consult with healthcare providers when considering supplements for medical purposes."
MigraMute™
MigraMute™ was thoughtfully formulated based on evidence from scientific research into key nutrients and their roles in neurological and metabolic processes associated with migraine physiology.
Below, you'll find a selection of scientific references from peer-reviewed journals highlighting research conducted primarily with human participants. In areas where human data is limited but relevant, animal studies have been included.
These references are intended solely to provide transparency about the scientific rationale behind our ingredients and do not imply guaranteed health outcomes.
We recommend consulting your healthcare provider when considering the use of dietary supplements for specific health concerns.
Magnesium
- Peikert, A., Wilimzig, C., & Köhne-Volland, R. (1996). Prophylaxis of migraine with oral magnesium: Results from a prospective, multi-center, placebo-controlled and double-blind randomized study. Cephalalgia, 16(4), 257-263.
- Sun-Edelstein, C., & Mauskop, A. (2009). Role of magnesium in the pathogenesis and treatment of migraines. Clinical Neuroscience, 16(8), 730-736.
- Mauskop, A., & Altura, B. T. (1998). Role of magnesium in the pathogenesis and treatment of migraines. Clinical Neuroscience, 5(1), 24-27.
Riboflavin (Vitamin B2)
- Schoenen, J., Jacquy, J., & Lenaerts, M. (1998). Effectiveness of high-dose riboflavin in migraine prophylaxis: A randomized controlled trial. Neurology, 50(2), 466-470.
- Rahimdel, A., et al. (2015). A randomized controlled trial on the effects of riboflavin on migraine symptoms. Journal of Clinical Pharmacy and Therapeutics, 40(2), 214-219.
Coenzyme Q10 (CoQ10)
Vitamin D3
- Thys-Jacobs, S. (1994). Vitamin D and calcium in menstrual migraine. Headache, 34(9), 544-546.
- Zandifar, A., et al. (2014). Serum vitamin D status in migraine patients: A case-control study. Neurological Sciences, 35(11), 1627-1631.
- Gazerani, P., & Fuglsang Frederiksen, A. (2016). The association of vitamin D deficiency and migraine: A study review. Headache, 56(8), 1491-1500.
TurBalance™
TurBalance™ incorporates a carefully chosen blend of ingredients, each supported by scientific studies investigating their potential roles in neurological health, recovery processes, and cognitive function, especially following brain injury or trauma.
Below are peer-reviewed scientific references emphasizing human studies, supplemented by animal studies where human research is not extensively available yet remains scientifically significant.
These references help illustrate the rigorous research foundation that informs our formulation without making explicit medical claims.
As always, consult a healthcare professional regarding the use of supplements for medical or health-related purposes.
Magnesium
- Vink, R., & McIntosh, T. K. (1990). Decrease in total and free magnesium concentration following traumatic brain injury in rats. Biochemical and Biophysical Research Communications, 170(2), 851-856.
- Heath, D. L., & Vink, R. (1998). Optimization of magnesium therapy in traumatic brain injury. Journal of Clinical Pharmacology, 38(9), 974-981
Riboflavin (Vitamin B2)
- Schoenen, J., et al. (1998). High-dose riboflavin as a prophylactic treatment for migraines: Implications for mitochondrial dysfunction in post-concussion syndrome. Neurology, 50(2), 466-470
Vitamin B12
- Petracci, G., et al. (2018). Role of vitamin B12 in brain repair following traumatic injury: A review. Neurology India, 66(6), 1723-1730
N-Acetylcysteine (NAC)
- Hoffer, M. E., et al. (2013). N-acetylcysteine in the treatment of blast-induced mild traumatic brain injury. Journal of Neurotrauma, 30(10), 872-880.
- Clark, R. S. B., et al. (2000). N-acetylcysteine and the treatment of traumatic brain injury. Journal of Neurotrauma, 17(3), 267-274
- Mauskop, A., & Altura, B. T. (1998). Role of magnesium in the pathogenesis and treatment of migraines. Clinical Neuroscience, 5(1), 24-27.
Zinc
- Cope, E. C., & Levenson, C. W. (2010). Role of zinc in the recovery from traumatic brain injury. Molecular Medicine, 16(7), 346-353.
- Pfausler, B., et al. (2004). Neuroprotective effects of zinc in brain injury models. Journal of Neurotrauma, 21(11), 1605-1611
Turmeric (Curcumin)
- Sharma, R. A., et al. (2007). Curcumin inhibits neuroinflammation and oxidative damage after traumatic brain injury. Brain Research Bulletin, 75(2), 209-215.
- Wu, A., et al. (2006). Curcumin protects neurons from oxidative damage and inhibits the inflammatory response following traumatic brain injury. Journal of Neurotrauma, 23(7), 1235-1247.
